Brock Purdy threw for 309 yards and two touchdowns on September 28, 2025, and still walked off the field with San Francisco’s first loss of the season. Three turnovers — two interceptions and a strip-sack that sealed the fourth quarter — erased what the 49ers built through the air. Jacksonville’s defense forced four takeaways, Parker Washington returned a punt 87 yards for a touchdown, and the Jaguars held on for a 26-21 win at Levi’s Stadium to move to 3-1.
Table of Contents
Game Information
Date
September 28, 2025
Venue
Levi’s Stadium, Santa Clara, CA
Attendance
70,495
Broadcast
FOX
Final Score
Jacksonville 26, San Francisco 21
Records
Jacksonville 3-1 · San Francisco 3-1
Scoring Summary
Quarter
Time
Team
Play
Score
Q1
8:33
SF
Eddy Piñeiro 26-yd FG
SF 3 – JAX 0
Q2
14:41
JAX
Travis Etienne Jr. 48-yd run (Little kick)
JAX 7 – SF 3
Q2
5:01
JAX
Hunter Long 4-yd pass from Lawrence (Little kick)
JAX 14 – SF 3
Q2
0:40
SF
Eddy Piñeiro 23-yd FG
JAX 14 – SF 6
Q2
0:00
JAX
Cam Little 26-yd FG
JAX 17 – SF 6
Q3
8:32
SF
McCaffrey 8-yd pass from Purdy (Purdy to Jennings, 2-pt conv.)
JAX 17 – SF 14
Q3
4:07
JAX
Cam Little 44-yd FG
JAX 20 – SF 14
Q3
2:22
JAX
Parker Washington 87-yd punt return (2-pt conv. failed)
JAX 26 – SF 14
Q4
7:41
SF
Jake Tonges 21-yd pass from Purdy (Piñeiro kick)
JAX 26 – SF 21
Team Stats
Stat
Jacksonville
San Francisco
Total Yards
325
389
Total Plays
63
63
Yards per Play
5.2
6.2
Passing Yards (net)
174
306
Comp / Att
21/31
22/38
Yards per Pass Attempt
5.6
7.8
Rushing Yards
151
83
Rushing Attempts
32
24
Yards per Rush
4.7
3.5
First Downs
18
22
— Passing
8
17
— Rushing
8
3
— Penalty
2
2
3rd Down Efficiency
4/14 (28.6%)
8/13 (61.5%)
4th Down Efficiency
1/1
0/1
Red Zone (Scored – Att)
1/2
1/3
Penalties
12 for 90 yds
5 for 54 yds
Turnovers
0
4
— Fumbles Lost
0
2
— Interceptions
0
2
Sacks – Yards Lost
0–0
1–3
Defensive / ST Touchdowns
1
0
Time of Possession
32:31
27:29
Passing Stats
Player
Team
C/ATT
YDS
AVG
TD
INT
SACKS
QBR
RTG
Trevor Lawrence
JAX
21/31
174
5.6
1
0
0–0
67.2
92.7
Brock Purdy
SF
22/38
309
8.1
2
2
1–3
53.7
79.8
Rushing Stats
Player
Team
CAR
YDS
AVG
TD
LG
Travis Etienne Jr.
JAX
19
124
6.5
1
48
Bhayshul Tuten
JAX
4
14
3.5
0
8
Brian Thomas Jr.
JAX
1
7
7.0
0
7
Trevor Lawrence
JAX
7
7
1.0
0
6
Parker Washington
JAX
1
-1
-1.0
0
—
JAX Total
32
151
4.7
1
48
Christian McCaffrey
SF
17
49
2.9
0
11
Brian Robinson Jr.
SF
5
21
4.2
0
7
Brock Purdy
SF
2
13
6.5
0
11
SF Total
24
83
3.5
0
11
Receiving Stats
Jacksonville Jaguars
Player
REC
TGT
YDS
AVG
TD
LG
Brenton Strange
6
7
45
7.5
0
11
Brian Thomas Jr.
5
7
49
9.8
0
14
Travis Hunter
3
5
42
14.0
0
28
Hunter Long
3
3
23
7.7
1
11
Bhayshul Tuten
1
1
8
8.0
0
8
LeQuint Allen Jr.
1
1
7
7.0
0
7
Travis Etienne Jr.
1
2
1
1.0
0
1
Tim Patrick
1
1
-1
-1.0
0
—
Parker Washington
0
2
—
—
0
—
Johnny Mundt
0
1
—
—
0
—
JAX Total
21
30
174
8.3
1
28
San Francisco 49ers
Player
REC
TGT
YDS
AVG
TD
LG
Christian McCaffrey
6
11
92
15.3
1
29
Jake Tonges
3
5
58
19.3
1
23
Ricky Pearsall
4
5
46
11.5
0
31
Kyle Juszczyk
3
3
32
10.7
0
18
Jauan Jennings
2
4
24
12.0
0
14
Demarcus Robinson
1
2
20
20.0
0
20
Luke Farrell
2
2
20
10.0
0
11
Kendrick Bourne
1
4
17
17.0
0
17
Skyy Moore
0
1
—
—
0
—
SF Total
22
37
309
14.0
2
31
Defensive Stats
Jacksonville Jaguars
Player
TOT
SOLO
SACKS
TFL
PD
QB HTS
TD
Tyson Campbell
9
4
0
0
0
0
0
Devin Lloyd
8
6
0
1
2
0
0
Foyesade Oluokun
7
2
0
0
0
0
0
Andrew Wingard
5
3
0
0
1
0
0
Antonio Johnson
5
2
0
0
0
0
0
DaVon Hamilton
4
0
0
0
0
0
0
Dennis Gardeck
3
3
0
0
0
0
0
Arik Armstead
2
2
1
1
0
0
0
Jourdan Lewis
2
2
0
0
0
0
0
Josh Hines-Allen
2
2
0
1
0
1
0
Dawuane Smoot
2
1
0
0
0
1
0
Austin Johnson
2
1
0
0
0
0
0
Jack Kiser
2
1
0
0
0
0
0
Travis Hunter
2
1
0
0
0
0
0
Eric Murray
2
0
0
0
0
0
0
Travon Walker
2
0
0
0
0
0
0
Maason Smith
2
0
0
0
1
0
0
Montaric Brown
1
1
0
0
0
0
0
Ross Matiscik
1
1
0
0
0
0
0
Quintin Morris
1
1
0
0
0
0
0
Jarrian Jones
1
1
0
0
0
0
0
Emmanuel Ogbah
1
0
0
0
0
1
0
JAX Total
66
34
1
3
4
3
1
San Francisco 49ers
Player
TOT
SOLO
SACKS
TFL
PD
QB HTS
TD
Dee Winters
10
9
0
1
1
0
0
Marques Sigle
8
6
0
0
1
0
0
Fred Warner
8
5
0
0
0
0
0
Deommodore Lenoir
6
5
0
1
0
0
0
Jason Pinnock
6
2
0
0
0
0
0
Darrell Luter Jr.
5
3
0
1
0
0
0
Sam Okuayinonu
4
2
0
1
0
0
0
Yetur Gross-Matos
3
0
0
0
0
0
0
Bryce Huff
2
2
0
1
0
0
0
Brayden Willis
2
2
0
0
0
0
0
Mykel Williams
2
1
0
0
0
0
0
Luke Gifford
2
0
0
0
0
0
0
Jordan Elliott
2
0
0
0
0
0
0
Christian McCaffrey
1
1
0
0
0
0
0
Chase Lucas
1
1
0
0
0
0
0
Kalia Davis
1
1
0
1
0
0
0
Colton McKivitz
1
0
0
0
0
0
0
Jake Tonges
1
0
0
0
0
0
0
Upton Stout
1
0
0
0
0
0
0
SF Total
66
40
0
6
2
0
0
Turnovers
Interceptions
Player
Team
INT
YDS
TD
Devin Lloyd
JAX
2
8
0
JAX Total
2
8
0
San Francisco — no interceptions
Fumbles
Player
Team
FUM
LOST
REC
Travis Hunter
JAX
1
0
0
LeQuint Allen Jr.
JAX
0
0
1
Foyesade Oluokun
JAX
0
0
1
Andrew Wingard
JAX
0
0
1
Luke Farrell
SF
1
1
0
Brock Purdy
SF
1
1
0
Christian McCaffrey
SF
1
0
1
Special Teams
Punt Returns
Player
Team
NO
YDS
AVG
LG
TD
Parker Washington
JAX
1
87
87.0
87
1
Skyy Moore
SF
1
16
16.0
16
0
Kick Returns
Player
Team
NO
YDS
AVG
LG
TD
Bhayshul Tuten
JAX
2
78
39.0
54
0
LeQuint Allen Jr.
JAX
2
25
12.5
25
0
Skyy Moore
SF
3
80
26.7
29
0
Kicking
Player
Team
FG
PCT
LG
XP
PTS
Cam Little
JAX
2/3
66.7%
44
2/2
8
Eddy Piñeiro
SF
2/2
100.0%
26
1/1
7
Little missed a 47-yard attempt with 7:41 remaining in the fourth quarter. San Francisco drove 92 yards for a touchdown on the ensuing possession to cut the deficit to five.
Punting
Player
Team
NO
YDS
AVG
TB
In 20
LG
Logan Cooke
JAX
5
237
47.4
2
1
58
Thomas Morstead
SF
2
91
45.5
0
0
51
Injuries
Player
Team
Position
Injury
Status
Travon Walker
JAX
DE
Wrist
Left in Q1, did not return
Eric Murray
JAX
S
Neck
Left in Q2, did not return
Ricky Pearsall
SF
WR
Knee
Left in Q3, did not return
Jacksonville generated at least three takeaways in each of its first four games of the 2025 season — producing more turnovers through Week 4 than the franchise had recorded across all of 2024. Purdy’s 309-yard, two-touchdown afternoon placed him among the game’s statistical leaders, yet three lost possessions told the truer story. The 26-21 win at Levi’s Stadium marked Jacksonville’s fifth road victory in 20 all-time trips to the West Coast.
Bobby A. Smith is a Senior Sports Analyst with over nine years of professional experience, specializing in forensic analysis of game strategy and player performance.
His work provides a definitive lens on a broad spectrum of professional sports, delivering expert commentary on the NFL, NBA, MLB, WNBA, Soccer, Boxing, Cricket, F1, and NASCAR. Unlike surface-level reporting, Bobby’s analysis is known for identifying the critical, game-deciding patterns that raw statistics often obscure. Every article is grounded in rigorous, fact-based research and an unwavering commitment to journalistic integrity.
